Nicole is one of the most versatile and recognizable voices in the comedy landscape today. Her latest Netflix special BIG BEAUTIFUL WEIRDO dropped this past December. Her previous Netflix special titled COMEDIANS OF THE WORLD brought together acclaimed comedic personalities from 13 international regions and was released in 2019. She is currently hosting Netflix’s Emmy nominated reality-competition baking series NAILED IT!. The show, which features amateur bakers failing to replicate Pinterest recipes, recently released its third season. She also regularly hosts the podcasts, Why Won’t You Date Me, and What the Tuck?. She can currently can be seen in NBC's recently released GRAND CREW as a series regular alongside Justin Cunningham, Aaron Jennings and Echo Kellum, which she has garnered positive reviews for already.

Her past work includes the Above Average web series PURSUIT OF SEXINESS, which she co-created and starred in alongside Sasheer Zamata. She also produced and stared in the scripted comedy series LOOSELY EXACTLY NICOLE, which debuted its first season on MTV and aired its second on the streaming platform Facebook Watch. Her other network television and feature work includes MIKE AND DAVE NEED WEDDING DATES, LADY DYNAMITE, PARTY OVER HERE, BOJACK HORSEMAN, and 30 ROCK.

Byer was an early standout and fan favorite on MTV’s hit series GIRL CODE, a strong and smart femaledriven comedy series that explicitly tackles the mysteries of womanhood. She is also an Upright Citizens Brigade alum who continues to cement her status as a force in standup comedy, regularly performing in cities across the country.